| Incidental findings | Scar from transfrontal resection |
| Signs | Large hands, protrusion lower jaw, inderdental separation, macroglossia |
| Differential diagnosis | Acromegaly |
| Function | Comment on disease activity: Sweating, hypertension, glycosuria, headache |
| Tests |
ECG, CXR - cardiomegaly
Oral GTT - failure of supression / paradoxical increase growth hormone IGF-1 level MR pituitary fossa T4, prolactin, testosterone. Triple stimulation if ?hypopit Formal perimetry |